Hand sanitizer use in pregnancy linked to childhood asthma, eczema, Health News, ET HealthWorld

Tokyo: A recent study found that the use of disinfectants by pregnant women may be a risk factor for asthma and eczema in their children.

The results of the study have been published in the journal “Occupational and Environmental Medicine”.

Disinfectants are frequently used in hospitals and other medical facilities, and the covid-19 pandemic has led to an increase in their use in medical settings and also more widely, including by the general population.

Exposure to disinfectants in the workplace has previously been associated with asthma and dermatitis in exposed workers, but few studies have examined the impact of disinfectant use during pregnancy and later development. allergic diseases in children.

The authors used data from 78,915 mother-child pairs who participated in the Japanese Environment and Children Study to determine whether mothers’ exposure to disinfectants in the workplace was associated with an increased risk of diagnosis. of allergic diseases in their children at the age of 3. .

The odds of children suffering from asthma or eczema were significantly higher if their mothers used disinfectants one to six times a week compared to the odds in children of mothers who never used disinfectants.

There was an exposure-dependent relationship between prenatal exposure to disinfectants and the likelihood of children suffering from these allergic conditions, with children of mothers exposed daily to disinfectants having the highest odds of a diagnosis – 26% more for asthma and 29% higher for eczema than children of mothers who have never been exposed to disinfectants.

There were no significant associations between the use of disinfectants and food allergies.

This is an observational study and as such cannot establish causation. The authors also noted some limitations, including that information on mothers’ use of disinfectants was self-reported with specific unidentified disinfectants. Diagnoses of allergic diseases in children have also been reported by mothers.

Nevertheless, the authors said: “Our results indicate that exposure (to disinfectants) during pregnancy exerts an effect on allergies in the offspring whether or not the mother returns to work when the child is 1 year old, and suggest an effect by exposure during pregnancy alone.

They added: “Given the current increased use of disinfectants to prevent new coronavirus infections, it is of great public health importance to determine whether prenatal exposure to disinfectants is a risk for disease development. allergic.”

Several mechanisms that may explain the increased risk of allergic disease in children following their mother’s exposure to disinfectants during pregnancy have been suggested by the authors.

They included microbial-mediated exposure (disinfectants impact the gut and skin microflora of the mother and subsequently the child), immune-mediated exposure (exposure to certain chemical compounds during pregnancy has an impact on the immune response of the fetus), postnatal exposure (children have inhaled or touched disinfectant molecules on their mother’s skin), or bias (mothers who frequently use medical disinfectants are susceptible to better medically informed and have better access to health care). (ANI)


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